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Urban Stormwater

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Magipics has created an illustration for the School of Agriculture, Food and Ecosystem Sciences at Melbourne University. The illustration was used as part of an ARC Discovery Grant application.

The project asks a fundamental global question: How much stormwater in cities is truly harvestable excess—after meeting the environmental flow needs of urban ecosystems—and how reliably can this excess support nonpotable demands through feasible storage and operation under current and future climates and land use?

Shown here is the rough hand-drawing and the finished artwork.

Rough hand-drawing:

Finished artwork:

NervAlign® Nerve Cuff

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Magipics is producing animations and illustrations for ReNerve, a medical device company that specializes in developing a range of ‘ready to use’ products for the repair or replacement of damaged peripheral nerves.
Shown here is an animated video, created in 2022, describing the “NervAlign® Nerve Cuff” product.
Due to confidentiality considerations, more recent product animations can not be shown at this stage.

Click on the image below to view the animation.


NervAlign® Nerve Cuff is a soft, tissue-compatible protective wrap used to protect repaired injured nerves. The product is developed by ReNerve for the surgical repair of transected (cut) and damaged nerves.

NervAlign® Nerve Cuff is designed for use in the repair of peripheral nerve injuries where there is no gap, or where gap closure can be achieved by flexion of the extremity. It is sutured into place to protect the nerve from negative inflammatory responses and scarring.

Mechanism of action of (E,E)-bisantrene

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Magipics has created an animation for Racura Oncology, a clinical biopharmaceutical company with a mission to silence cancer.

The animation describes a novel therapeutic approach to target MYC-driven cancers using Racura Oncology’s (E,E)-bisantrene drug. The drug has been shown in preclinical studies to bind and stabilise a normally unstable G-quadruplex. By locking this structure in place, (E,E)-bisantrene is believed to silence MYC transcription, evidenced through suppressed MYC mRNA levels in preclinical studies.

This mechanism represents a novel therapeutic approach being investigated by Racura Oncology to target MYC-driven cancers, with the potential to improve patient outcomes.

Click on the image below to view the animation.

Nanocomposite materials

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Magipics has produced an illustration for Trinity College, Dublin University. It depicts direct laser writing, using 2 photon polymerisation, of self-assembled nanocomposite materials.

Magipics is currently creating illustrations and animations for Trinity College on this and related topics.

Using fabrication parameters, Teodora Faraone, Colm Delaney, and co-workers are able to finely tune the interparticle spacing. They exploit this to generate wide gamut reflected color in the aqueous state and employ it in stimuli-responsive polymers for responsive color changes.

The illustration was accepted as cover picture in the “Advanced Materials” journal, volume 37, issue 43. Advanced Materials is one of the world’s most prestigious journals, and is the home of choice for best-in-class materials science for more than 30 years.

Vitradel drug delivery

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Magipics has created an animation for Vitradel Pty Ltd to illustrate the back-of-eye delivery of a drug. The technology allows for delivery of small organic drugs as well as large biological molecules.


The product, comprising a blend of monomers, is administered as a liquid. Following injection into the eye in situ polymerisation occurs, forming linkages that allow for a tunable drug release. The remaining molecular scaffold undergoes rapid biodegradation after the drug is released, leaving no residue.

The animation can be viewed on Vitradel’s website.

Clarity comic book

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Magipics has created a comic book, aimed at children under 12 years with neuroblastoma cancer, for Clarity Pharmaceuticals. The book explains a cancer treatment product and the trial in a friendly reassuring manner.

Shown here is page 1 of the comic book.

Clarity Pharmaceuticals is a clinical stage radiopharmaceutical company developing next-generation products to address the growing need for the use of radiopharmaceuticals in oncology.

Magipics created the finished artwork (including all character design etc.) based on a rough concept supplied by the client.

Green Infrastructure

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Magipics has created an illustration for The Retrofit Lab at Melbourne University to graphically sum up the concept “Re-Imagining Streets With Green Infrastructure”.

As described on the Retrofit Lab web page:

“This project’s overall objective is to demonstrate how streets can be adapted to improve resilience to heatwaves, drought and flooding, while improving their safety, liveability and sociability.

It will work with local residents and stakeholders to develop and evaluate designs for deep retrofitting of streets as integrated green infrastructure – how can we add trees to existing streets, and what could that look like? The outcome will be robust evidence to inform more ambitious policy change in urban greening, and solutions to address key barriers to implementation.

As part of this project, we are hosting ‘co-design’ workshops, working with local residents and stakeholders to develop a shared vision of greener streets at each site.”

Denteric

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Precision immunotherapies for chronic Porphyromonas gingivalis infections

Magipics has produced animated videos for Denteric, a Melbourne-based clinical-stage biotech company. Denteric is developing therapies with the potential to treat diseases such as periodontal disease.

Periodontitis is a chronic oral disease that affects 1 in 3 adults and is caused by the bacterium Porphyromonas gingivalis (Pg). The animations describe the infection mechanism of Porphyromonas gingivalis, and Denteric’s potential immunotherapy. The therapy is administered as a simple injection. It stimulates the immune system to produce antibodies against Porphyromonas gingivalis to help reduce periodontal disease.

The animations can be viewed on Denteric’s website www.denteric.com:
Pg and it’s role in periodontitis
GPV381 – An immunotherapy targeting major virulence factors produced by P. gingivalis (Pg)


64/67Cu-SAR-bisPSMA: A Next-Generation PSMA Theranostic

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Magipics has continued producing animations and illustrations for Clarity Pharmaceuticals. The most recent one describes SAR-bisPSMA, a next generation, highly targeted theranostic radiopharmaceutical. It has increased specificity and in-vivo stability, and is being developed for diagnosing, staging and subsequently treating cancers that express Prostate Specific Membrane Antigen (PSMA).

Prostate cancer is the second most common cancer in men and the 5th leading cause of death in men worldwide. Early detection and better treatment options for prostate cancer are therefore of vital importance.

The animation and illustrations can be viewed on the Clarity Pharmaceuticals website.

Aravax MoA

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Magipics has produced a biomedical animation for Aravax describing the mechanism of action of PVX108, a next generation immunotherapy for the treatment of peanut allergy.
As stated on the Aravax website (aravax.com.au): “Aravax is a clinical-stage biotechnology company developing the first safe, convenient and disease-modifying treatment for peanut allergy. Aravax uses proprietary technology to precisely reset the immune system to tolerate allergens without evoking allergic reactions during treatment. The company is headquartered in Melbourne, Australia.
Following successful Phase 1 trials, Aravax’s lead product PVX108 has received FDA clearance to commence Phase 2 clinical trials in the United States. PVX108 is being developed to become the first safe and convenient treatment for peanut allergy.”

Mats Bjorklund at Magipics has a strong scientific background in molecular biology and cell biology with a PhD in Biotechnology. Creating accurate visuals illustrating complex biomedical topics such as these are thus easily handled.

The animation can be viewed on the Aravax website.