Magipics has produced animated videos for a large pharmaceutical corporation. Shown here is an extract from one of these animations. It illustrates a common affinity chromatography concept.
Briefly, antigen molecules (shown in purple) are immobilized on a microporous resin. A solution containing a mixture of proteins, including antibodies (blue), is then passed through the resin, whereupon the antibodies bind specifically to the antigen. Other proteins pass through. A pure solution of antibodies is finally generated by adding a buffer that causes the antibodies to desorb from the antigen molecules.
The graphic representations of the molecules were created using publicly available crystallographic data.
Click on the image below to view the animation.
